Flashcards · Biology
Health and Infectious Disease
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How does the WHO define health?
A state of complete physical, mental and social well-being, not just the absence of disease.
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What is a communicable disease?
A disease caused by a pathogen that can be spread.
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Give two examples of communicable diseases.
Cholera, tuberculosis, malaria or HIV.
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What is a non-communicable disease?
A disease that is not caused by a pathogen and cannot be passed on.
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Give two examples of non-communicable diseases.
Cancer, heart disease, diabetes or cystic fibrosis.
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What is a pathogen?
A microorganism that causes disease.
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Name four types of pathogen.
Viruses, bacteria, fungi and protists.
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Why does HIV increase the risk of TB?
It destroys white blood cells, so the immune system is weaker.
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How can a communicable disease cause a non-communicable disease?
HPV infection can lead to cervical cancer.
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How does poor nutrition affect susceptibility to disease?
It weakens the immune system.
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What is a positive correlation?
As one variable increases, the other also increases.
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Does correlation prove cause?
No. Other factors might affect both variables.
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Give two factors that affect health.
Diet, stress, poverty, genes, or exposure to pathogens.
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Can mental health affect physical health?
Yes. Stress can weaken the immune system.
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Is a person with no disease but who is lonely fully healthy, according to the WHO?
No. Social well-being is also needed.
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Common mistake about non-communicable diseases?
Saying they are caused by pathogens. They are not.
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Name the four types of pathogen.
Viruses, bacteria, fungi and protists.
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Which is the smallest type of pathogen?
A virus.
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Are viruses made of cells?
No.
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How do bacteria reproduce?
By dividing, which can happen as often as every 20 minutes.
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What is a toxin?
A poison made by a pathogen that damages the host's tissues.
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What pathogen causes cholera?
A bacterium, Vibrio cholerae.
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What is the main symptom of cholera?
Severe watery diarrhoea, leading to dehydration.
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What pathogen causes tuberculosis?
A bacterium, Mycobacterium tuberculosis.
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What does TB do to the body?
It damages the lungs.
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What kind of organism causes Chalara ash dieback?
A fungus.
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What are the symptoms of ash dieback?
Leaf loss and lesions on the bark.
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What type of pathogen causes malaria?
A protist, called Plasmodium.
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What does malaria damage?
The blood and the liver.
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What does HIV destroy?
White blood cells.
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What is AIDS?
The stage when the immune system fails because of HIV.
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Common mistake about HIV and AIDS?
Saying that they are the same. HIV is the virus, and AIDS is the condition that develops.
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How is cholera spread?
In water that has been contaminated with sewage.
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Name two ways of preventing cholera.
Clean drinking water and sewage treatment, or hand washing.
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How is TB spread?
In droplets in the air from coughs and sneezes.
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Name two ways of reducing the spread of TB.
Isolating infected people, ventilation, vaccination or treatment.
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How is Chalara ash dieback spread?
By airborne spores, and on imported trees.
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How can the spread of ash dieback be slowed?
Controlling imports, and destroying infected trees.
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What is a vector?
An organism that carries a pathogen from one host to another.
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What is the vector for malaria?
The female Anopheles mosquito.
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Name two ways of preventing malaria.
Mosquito nets, killing mosquitoes or draining standing water.
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Why are insecticide-treated nets effective?
They stop mosquitoes biting at night, and kill mosquitoes that land on them.
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Why does draining standing water help?
Mosquitoes breed in water, so there are fewer of them.
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Why is TB spread more where there is overcrowding?
There are more people to breathe in the infected droplets.
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What does the BCG vaccine protect against?
Tuberculosis.
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Who showed that cholera spread through water in 1854?
John Snow.
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Why does treating infected people reduce spread?
They have fewer pathogens to pass on, so they are less likely to infect others.
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Common mistake about malaria?
Saying that mosquitoes cause malaria. They carry the protist that causes it.
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What is an STI?
An infection that is passed on by sexual contact.
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What causes chlamydia?
A bacterium.
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Why can chlamydia spread widely?
Many people have no symptoms, so they do not know they are infected.
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What can untreated chlamydia cause?
Infertility, because of pelvic inflammatory disease.
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How is chlamydia treated?
With antibiotics.
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What causes HIV?
A virus.
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Name three ways in which HIV is spread.
Sexual contact, sharing needles and from a mother to her baby.
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What does HIV do in the body?
It destroys white blood cells.
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Is there a cure for HIV?
No, but antiretroviral drugs control it.
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How does a condom reduce the spread of STIs?
It stops body fluids passing between people.
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What is screening?
Testing people with no symptoms to find an infection early.
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Why are needle exchange schemes used?
So that people do not share needles, which spreads HIV.
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How can HIV be prevented from passing from mother to baby?
Drugs for the mother, caesarean delivery, and avoiding breastfeeding.
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Why is donated blood tested?
To stop HIV from being passed on in transfusions.
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Why do antibiotics not cure HIV?
HIV is a virus, and antibiotics only work on bacteria.
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Common mistake about HIV?
Thinking it can be caught by touching or hugging. It is spread through body fluids.
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What causes most stomach ulcers?
The bacterium Helicobacter pylori.
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Where does H. pylori live?
In the mucus lining of the stomach.
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How does H. pylori survive stomach acid?
It makes an enzyme that produces ammonia, which neutralises the acid.
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How are stomach ulcers formed?
The bacteria damage the lining, so acid and enzymes attack the exposed tissue.
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How does H. pylori spread?
By oral transmission, in contaminated food, water or saliva.
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How is an ulcer caused by H. pylori treated?
With antibiotics and a drug that reduces stomach acid.
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Who showed that H. pylori causes ulcers?
Barry Marshall and Robin Warren.
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What did Marshall do to prove it?
He swallowed a culture of the bacteria.
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What did doctors think caused ulcers before?
Stress, spicy food and excess acid.
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What type of pathogen causes Ebola?
A virus.
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What does Ebola cause?
A haemorrhagic fever.
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How is Ebola spread?
By contact with the body fluids of an infected person or animal.
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Name two ways of reducing the spread of Ebola.
Isolating patients, protective clothing for health workers, safe burials or vaccination.
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Why is contact tracing important in an outbreak?
It finds people who may be infected, so they can be watched and isolated.
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Is Ebola spread through the air?
No. It spreads by direct contact with body fluids.
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Common mistake about ulcers?
Saying that stress is the main cause. Most are caused by H. pylori.
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What is a virus made of?
Genetic material (DNA or RNA) in a protein coat.
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Can a virus reproduce on its own?
No. It needs a host cell.
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What is the protein coat of a virus called?
The capsid.
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Why can a virus only infect certain cells?
Its surface proteins only fit the receptors on certain cells.
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What are the stages of the lytic pathway?
Attachment, entry, replication, assembly and lysis.
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What happens at lysis?
The host cell bursts and releases new viruses.
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What happens in the lysogenic pathway?
The viral DNA joins the host's chromosome and is copied when the cell divides.
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What is a provirus?
Viral DNA that has been integrated into the host's chromosome.
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Does the host cell survive in the lysogenic pathway?
Yes, and it divides normally.
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What can start the lytic pathway from the lysogenic one?
A trigger, such as stress or damage.
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Why is a hidden virus difficult for the immune system to find?
It is not making any viral proteins.
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Why do antibiotics not work on viruses?
Viruses do not have the structures and processes that antibiotics attack.
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Which virus can hide in the lysogenic state and is not curable?
HIV.
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How many viruses after 2 rounds if each cell releases 50?
2500.
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What is the best way to prevent viral disease?
Vaccination.
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Common mistake about viruses?
Saying that they are living cells. They are not cells.