Flashcards · Biology · Human Defences and Immunity
Immunisation
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What is a vaccine?
A preparation of an inactive or weakened pathogen that makes the body immune.
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Why does a vaccine not make you ill?
The pathogen is inactive, so it cannot reproduce or cause disease.
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What does a vaccine contain that triggers the immune response?
The antigens of the pathogen.
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What does the body make after a vaccine?
Antibodies and memory lymphocytes.
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Why is the response to a real infection faster after vaccination?
Memory lymphocytes make a secondary response.
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What is a booster dose?
An extra dose given to keep the level of memory lymphocytes high.
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Why does the flu vaccine change each year?
The flu virus mutates, so its antigens change.
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Who developed the first vaccine?
Edward Jenner, for smallpox.
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When was smallpox declared eradicated?
1980.
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What is a placebo?
A harmless substance with no effect, used for comparison in a trial.
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Why is a placebo used in a vaccine trial?
To compare the effect of the vaccine with no vaccine.
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Give one example of a disease that has been controlled by vaccination.
Smallpox, polio, measles or diphtheria.
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How is the measles vaccine different from the flu vaccine?
Measles changes very little, so one vaccine works for life.
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Is a vaccine a treatment for an infection that has begun?
No. It prevents infection in future.
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What is the difference between inactive and weakened pathogens?
Inactive ones are killed, weakened ones are alive but harmless.
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Common mistake about vaccines?
Saying that a vaccine gives the person the disease. It does not, because the pathogen is inactive.