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Biology · OCR Paper 2

Inheritance

How genetic information is passed from one generation to the next, from the genome, genes, alleles and variants to the causes of variation, mutations and their effects, the advantages and disadvantages of asexual and sexual reproduction, the role of meiosis in making haploid gametes, single gene crosses and sex determination, and the work of Mendel. Matches OCR GCSE Biology A (Gateway Science) B5.1a to B5.1m. Genes, the genome and phenotype, variation and mutations, meiosis, and single gene inheritance are for both Combined Science and separate Biology. Asexual and sexual reproduction (B5.1f) and Mendel (B5.1m) are for separate Biology only. Genetic variants and phenotype (B5.1e) is for separate Biology and the Higher tier only.

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Key terms in this chapter

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Gene
A section of DNA that codes for a protein.
Allele
A different version of a gene, also called a variant.
Genome
The entire genetic material of an organism.
Genotype
The alleles that an organism has for a gene.
Phenotype
The observable features of an organism, caused by the genotype and the environment.
Dominant
Describes an allele that shows its effect even when only one copy is present.
Recessive
Describes an allele whose effect only shows when there are two copies.
Homozygous
Having two identical alleles of a gene.
Heterozygous
Having two different alleles of a gene.
Variation
The differences between individuals of the same species.
Discontinuous variation
Variation in which individuals fall into distinct categories.
Continuous variation
Variation in which a feature can have any value within a range.
Mutation
A random change in the base sequence of DNA.
Variant
A different version of a gene, which arose from a mutation.
Mutagen
Something that increases the rate of mutation, such as ionising radiation.
Histogram
A bar chart for continuous data, in which the bars touch.
Mode
The value that occurs most often.
Environment
The surroundings and conditions in which an organism lives.
Coding DNA
The parts of the DNA that code for proteins, which are the genes.
Non-coding DNA
Parts of the DNA that do not code for proteins, but may control how genes are used.
Gene expression
The way in which a gene is used to make its protein.
Transcription
The copying of the DNA of a gene into mRNA.
Active site
The part of an enzyme where the substrate binds.
Enzyme-substrate complex
The enzyme and its substrate joined together.
Frameshift
A change in all of the triplets after an addition or deletion of bases.
Variant
A different version of a gene, which arose from a mutation.
Protein structure
The shape of a protein, which depends on the order of its amino acids.
Asexual reproduction
Reproduction involving one parent, with no gametes, producing genetically identical offspring.
Sexual reproduction
Reproduction involving the fusion of gametes from two parents, producing genetically different offspring.
Clone
A genetically identical copy of an organism.
Environmental pressure
A factor such as disease, predators or a change in climate, which affects survival.
Offspring
The young produced by a parent organism.
Runner
A stem that grows along the ground and makes new plants, as in strawberries.
Mitosis
Cell division that gives two genetically identical cells.
Meiosis
Cell division that gives four genetically different gametes.
Colonise
To spread into and settle in a new habitat.
Meiosis
A type of cell division that produces four genetically different haploid gametes.
Haploid
Having one set of chromosomes, as in a gamete.
Diploid
Having two sets of chromosomes, as in a body cell.
Gamete
A sex cell, such as a sperm cell or an egg cell.
Fertilisation
The fusion of a male gamete and a female gamete.
Zygote
The cell formed when two gametes fuse. It is diploid.
Embryo
An early stage of development of an organism, formed from the zygote.
Chromosome
A long molecule of DNA that carries genes.
Genetic variation
Differences in the genes of individuals of the same species.
Single gene cross
A cross that looks at the inheritance of one gene.
Punnett square
A grid that shows the possible combinations of gametes in a cross.
Genotype
The alleles that an organism has for a gene.
Phenotype
The feature that an organism shows.
Carrier
A person who has a recessive allele but does not show the disorder.
Probability
The chance that an event will happen.
Sex chromosomes
The pair of chromosomes that decides the sex of a person: XX in a female and XY in a male.
Ratio
A comparison of numbers, such as 3 : 1.
Test cross
A cross with a homozygous recessive individual to find an unknown genotype.
Blending inheritance
The idea that the features of parents mix in their offspring.
Pure-breeding
Producing offspring that are always the same as the parent.
Cross-pollination
The transfer of pollen from one plant to the flower of another plant.
P generation
The parental generation in a cross.
F1 generation
The first generation of offspring from a cross.
F2 generation
The offspring from the cross of F1 individuals.
Inherited factor
Mendel's name for what we now call a gene.
Chromosome
A long molecule of DNA that carries genes.
Genome
The entire genetic material of an organism.