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Biology · AQA Paper 2

Hormonal Coordination in Humans

How the endocrine system coordinates the body with hormones, how insulin and glucagon control blood glucose and what goes wrong in diabetes, how the kidneys keep the water and nitrogen balance and what happens in kidney failure, and how hormones control the menstrual cycle, contraception and treatment for infertility. Matches AQA topic 4.5.3 (hormonal coordination in humans). Water and nitrogen balance and kidney failure (4.5.3.3) are for separate Biology only; the rest is for Combined Science and separate Biology, with the interaction of the menstrual cycle hormones, glucagon, ADH, deamination and the use of hormones to treat infertility for the Higher tier only.

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Lessons

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Key terms in this chapter

All 46, gathered from every lesson.

Hormone
A chemical messenger carried in the blood.
Endocrine gland
A gland that releases hormones into the blood.
Target organ
An organ with receptors that respond to a particular hormone.
Pituitary gland
The master gland that releases hormones controlling other glands.
Thyroid gland
The gland in the neck that releases thyroxine.
Adrenal gland
A gland above the kidney that releases adrenaline.
Blood glucose concentration
The amount of glucose in the blood.
Insulin
The hormone that lowers the blood glucose concentration.
Glucagon
The hormone that raises the blood glucose concentration (Higher tier).
Pancreas
The organ that releases insulin and glucagon.
Glycogen
The carbohydrate in which the liver stores glucose.
Diabetes
A disease in which the blood glucose concentration is not controlled properly.
Type 1 diabetes
Diabetes in which the pancreas does not make enough insulin.
Type 2 diabetes
Diabetes in which the body cells stop responding to insulin.
Osmosis
The movement of water across a partially permeable membrane from a dilute to a concentrated solution.
Urea
A waste substance made in the liver from excess amino acids, removed in the urine.
Urine
The liquid made by the kidneys that contains urea, excess water and excess ions.
Filtration
The removal of small molecules from the blood into the filtrate in the kidney.
Selective reabsorption
The taking back into the blood of useful substances such as glucose, some ions and some water.
Filtrate
The liquid that has been filtered out of the blood in the kidney.
Deamination
The removal of the nitrogen-containing part of an amino acid in the liver, forming ammonia (Higher tier).
ADH
The hormone from the pituitary gland that makes the kidney tubules more permeable to water (Higher tier).
Kidney failure
The kidneys can no longer remove urea or control the water and ion balance.
Dialysis
A treatment that uses a machine to remove urea and excess ions from the blood.
Dialysis fluid
The fluid on the other side of the membrane, with the same glucose and useful ions as normal blood.
Partially permeable membrane
A membrane that lets some substances through but not others.
Transplant
An operation that replaces a failed organ with a healthy organ from a donor.
Donor
A person who gives an organ to another person.
Rejection
The attack by the immune system on a transplanted organ.
Immunosuppressant
A drug that reduces the activity of the immune system.
FSH
Follicle stimulating hormone, which makes an egg mature in an ovary.
LH
Luteinising hormone, which stimulates ovulation.
Oestrogen
The main female reproductive hormone, made in the ovaries.
Progesterone
A hormone that maintains the lining of the uterus.
Testosterone
The main male reproductive hormone, made by the testes, which stimulates sperm production.
Ovulation
The release of a mature egg from an ovary.
Menstruation
The loss of the lining of the uterus, which is a period.
Follicle
The structure in the ovary in which an egg matures.
Contraception
A method of preventing pregnancy.
Combined pill
A contraceptive pill containing oestrogen and progesterone.
Implant
A small rod put under the skin that releases progesterone slowly.
Condom
A barrier method that stops sperm reaching an egg and protects against infection.
IUD
A small device put in the uterus that prevents pregnancy.
Infertility
Difficulty in conceiving a child.
IVF
In vitro fertilisation: fertilising an egg with sperm in a laboratory dish (Higher tier).
Embryo
A ball of cells that grows from a fertilised egg.